Types of Uterine Fibroids
Uterine fibroids are classified according to their location within or around the uterus. The type of fibroid determines the symptoms it is likely to cause and influences the treatment options available. Understanding the different types is an important step in making informed decisions about your care.
Fibroid Types at a Glance
Fibroids are named for their position relative to the uterine wall.
Intramural
Within the muscular wall
Grow within the muscular wall of the uterus. The most common type.
Submucosal
Into the uterine cavity
Project inward into the uterine cavity. Most affect bleeding.
Subserosal
On the outer surface
Grow outward from the outer surface of the uterus.
Pedunculated
Attached by a stalk
Attached to the uterus by a narrow stalk (pedicle).
Intramural Fibroids
Intramural fibroids are the most common type, accounting for approximately 70% of all uterine fibroids. They develop within the myometrium, the muscular wall of the uterus, and can range in size from a few millimetres to over 20 centimetres in diameter.
Small intramural fibroids may cause no symptoms at all. As they grow, however, they can cause heavy menstrual bleeding, pelvic pressure, urinary frequency, and abdominal distension. Very large intramural fibroids that extend towards the uterine cavity (intramural-submucosal) are particularly likely to cause heavy periods.
Intramural fibroids respond well to uterine fibroid embolisation (UFE) and can also be treated with myomectomy or, in severe cases, hysterectomy. The choice of treatment depends on the size and number of fibroids, the severity of symptoms, and the patient’s individual preferences and reproductive plans.
Submucosal Fibroids
Submucosal fibroids grow just beneath the endometrium (the inner lining of the uterus) and project into the uterine cavity. Although they are the least common type, they are clinically the most significant because even small submucosal fibroids can cause pronounced symptoms.
The hallmark symptom of submucosal fibroids is heavy menstrual bleeding (menorrhagia). By distorting the endometrium, these fibroids increase the surface area of the lining and disrupt normal endometrial shedding, leading to prolonged, heavy, and often irregular periods. Submucosal fibroids are also the type most strongly associated with reproductive difficulties, including infertility and recurrent miscarriage.
Treatment options for submucosal fibroids include hysteroscopic resection (removal through the cervix without abdominal incisions), UFE, and medical management. Hysteroscopic resection is particularly effective for smaller submucosal fibroids that are predominantly within the uterine cavity.
Subserosal Fibroids
Subserosal fibroids develop on the outer surface of the uterus, growing outward into the pelvic cavity. Because they do not typically distort the uterine cavity, they are less likely to cause heavy menstrual bleeding than submucosal or intramural fibroids.
Instead, subserosal fibroids tend to cause pressure-related symptoms. As they enlarge, they can press on neighbouring organs, leading to urinary frequency (when pressing on the bladder), constipation (when pressing on the rectum), back pain, and abdominal distension. Very large subserosal fibroids can grow to a considerable size before causing symptoms, as they have space to expand within the pelvic and abdominal cavity.
UFE is an effective treatment for subserosal fibroids, as is laparoscopic or open myomectomy. The treatment approach is guided by the size and location of the fibroid and the patient’s symptoms and preferences.
Pedunculated Fibroids
Pedunculated fibroids are fibroids that are attached to the uterus by a narrow stalk, or pedicle. They can be either subserosal (hanging from the outer surface of the uterus into the pelvic cavity) or submucosal (projecting into the uterine cavity on a stalk).
The symptoms of pedunculated fibroids depend on their size and location. Subserosal pedunculated fibroids may cause pressure symptoms, while submucosal pedunculated fibroids are more likely to cause heavy bleeding. A unique risk associated with pedunculated fibroids is torsion, where the fibroid twists on its stalk, cutting off its blood supply and causing sudden, severe pelvic pain that requires urgent medical attention.
Pedunculated submucosal fibroids can sometimes be removed hysteroscopically. Pedunculated subserosal fibroids with a narrow stalk may not be the best candidates for UFE due to a small risk of the fibroid detaching after embolisation; however, this is assessed on a case-by-case basis during your consultation.
How Fibroid Type Affects Treatment
The location of fibroids within the uterus is one of the most important factors in determining the most appropriate treatment. A thorough assessment with MRI imaging allows our team to accurately classify each fibroid and develop a tailored treatment plan.
For example, small submucosal fibroids may be best treated with hysteroscopic resection, while multiple intramural fibroids are often ideally suited to UFE. Large subserosal fibroids may require surgical removal if they are causing significant pressure symptoms. In many cases, a combination of approaches may be recommended.
At the North London Fibroid Clinic, we offer the full range of treatment options and work with each patient to develop a personalised plan based on their specific fibroid type, symptom profile, and individual goals. To discuss your options, visit our treatment options page or book a consultation.
Frequently Asked Questions
References
- NHS — Fibroids. Available at: https://www.nhs.uk/conditions/fibroids/
- NICE Clinical Knowledge Summaries — Fibroids. Available at: https://cks.nice.org.uk/topics/fibroids/
- Munro MG, Critchley HOD, Fraser IS. The two FIGO systems for normal and abnormal uterine bleeding symptoms and classification of causes of abnormal uterine bleeding in the reproductive years. International Journal of Gynaecology and Obstetrics. 2018;143(3):393–408.
- Stewart EA. Uterine Fibroids. New England Journal of Medicine. 2015;372(17):1646–1655.
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